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Not merely its quantity but additionally the useful Qualities of Hb impact effectiveness. This really is illustrated because of the observation that an increased Hb-O2 affinity favors O2 loading in the lung and survival in an hypoxic setting (Eaton et al., 1974; Hebbel et al., 1978), whereas a lessened Hb-O2 affinity favors the discharge of O2 from